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HPE and NVIDIA’s Collaboration Unlocks a Range of AI Use Cases, Centering Speed, Performance, Efficiency, and Security

HPE is announcing that through new enhancements to its NVIDIA AI Computing by HPE portfolio—a collaboration to deliver AI factor solutions that accelerate AI adoption—enterprises benefit from a series of integrations that better enable agility amid the AI boom. Featuring stronger integrations with NVIDIA AI Enterprise, the latest NVIDIA AI models and NVIDIA Blueprints, along with NVIDIA Blackwell accelerated computing, HPE democratizes greater AI innovation with an emphasis on ease.

HPE and NVIDIA’s expanded collaboration aims to enable generative, agentic, and physical AI workloads for enterprise customers of all sizes, supporting these efforts throughout the entire AI lifecycle.

“HPE is committed to empowering enterprises with the tools they need to succeed in the age of AI,” said Cheri Williams, senior vice president and general manager for private cloud and flex solutions at HPE. “Our collaboration with NVIDIA continues to push the boundaries of innovation, delivering solutions that unlock the value of generative, agentic, and physical AI while addressing the unique demands of enterprise workloads.

As part of this effort, HPE ProLiant Compute servers are now accelerated by the NVIDIA Blackwell architecture, enabling enterprises to meet the growing demands of AI workloads. Innovating in flexibility, power, and security, HPE ProLiant Compute servers accelerated by  NVIDIA Blackwell reduces IT efforts spent on server management by up to 75% and cuts downtime by 4.8 hours per server, annually, according to the companies. This is ideal for AI use cases such as:

  • Robotics and industrial
  • Visual computing, such as quality control monitoring and autonomous vehicles
  • Simulation
  • 3D modeling
  • Digital twins
  • Enterprise applications

Additionally, this announcement unveils support for new NVIDIA reasoning models and video blueprint within HPE Private Cloud AI—a turnkey AI factory solution for the enterprise co-developed with NVIDIA. Supported models include:

This expanded support not only drives greater, faster innovation for AI, it also ensures enterprises maintain control over their data with HPE Private Cloud AI.

“With the combination of HPE ProLiant servers and expanded capabilities in HPE Private Cloud AI, we’re enabling organizations to embrace the future of AI with confidence and agility,” added Williams.

“Enterprises need flexible, efficient infrastructure to keep pace with the demands of modern AI,” said Justin Boitano, vice president of enterprise AI at NVIDIA. “With NVIDIA RTX PRO 6000 Blackwell GPUs in HPE’s 2U ProLiant servers, enterprises can accelerate virtually every workload on a single, unified, enterprise-ready platform.”

To learn more about HPE and NVIDIA’s continued collaboration, please visit https://www.hpe.com/us/en/home.html or https://www.nvidia.com/en-us/.

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